Management of fulminant myocarditis: peripheral venoarterial extracorporeal membranous oxygenation and associated complications

Abstract Background Fulminant Myocarditis (FM) leads to cardiogenic shock with multi-organic dysfunction, being peripheral venoarterial extracorporeal membranous oxygenation (VA-ECMO) a rescue technique. Despite growing experience, it is still related several complications. We aim appraise the management of patients FM and adverse events associated VA-ECMO. Methods conducted retrospective study in ECMO centre Portugal, which included 15 diagnosed managed on VA-ECMO from 2008 2018. Hemorrhage or infection cardiac device site, tamponade, limb ischemia, ischemic stroke, cerebral hemorrhage, severe hemolysis accidental decannulation were considered major Results For sample characteristics resumed complications, see Table. Inotropic mechanical ventilation support transversal all, only one patient extubated before decannulation. Six received renal replacement therapy, whom half recovered function remaining died. operated average for 8,5 days (range, 1 20 days). 3 had concomitant Impella heart pump them third assistance Intra-Aortic Ballon pump. Major complications observed 9 (60%), stroke most common. Limb 5 patients, longer duration (limb ischemia vs non-limb ischemia; 12,8±4,9 vs. 6,8±6,5 Two presented hemorrhage all fatal outcome. Infection not observed. Conclusion The common both apparently mortality. Differently, site tamponade less frequent but ominous Overall, can be serious hinder recovery discharge. Funding Acknowledgement Type funding sources: None.